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Original Research | Medicine | Volume 15 Issue 7, July 2026 | Pages: 1212 - 1216 | India
Aging Hearts at Risk: Clinical Spectrum and in-Hospital Mortality in Geriatic Acute Coronary Syndrome
Abstract: Background: Acute Coronary Syndrome (ACS) is a leading cause of morbidity and mortality worldwide, particularly among the elderly population. Aging is associated with increased cardiovascular risk factors, comorbidities and atypical presentations complicating both diagnosis and management. Aim and Objectives: This study aims to evaluate the clinical presentation, ECG, Echocardiography and outcomes of ACS in elderly patients. Material and Methods: This prospective observational study was conducted at a tertiary care center from October 2021 to September 2022. A total of 50 elderly patients (aged ≥65 years) diagnosed with ACS were included. Statistical analysis was conducted using Student's t-test and the chi-square test, considering p<0.05 as significant. Results: Among the 50 patients 62% were male and 38% were female. The majority (42%) were aged 65-69 years with a mean age of 71.78±5.13 years. The most common presenting symptom was epigastric pain (82%), followed by breathlessness (64%). Hypertension (62%) and tachycardia (44%) were the most common clinical findings. ECG findings revealed ST elevation in 42% and T-wave inversion in 38%. On 2D echocardiography inferior wall involvement was most frequent (24%) followed by anterior wall involvement and global LV hypokinesia (22%) each. Anterolateral and posterior wall involvement were seen in 14% and 12% of patients respectively. 80.9% of STEMI patients had an ejection fraction (EF) of 21-40% followed by 14.3% with EF >40%. Among NSTEMI patients 75.86% had an EF of 21-40% while 24.14% had an EF >40%. Overall mortality was 26% (13 of 50 patients). Mortality was notably higher among patients presenting with cardiogenic shock and congestive heart failure. Conclusion: ACS is a major public health concern in the elderly with rising incidence and frequent atypical presentations that delay diagnosis and treatment. Early intervention and individualized management are essential to improve outcomes. There is a need for elderly-specific clinical trials to optimize treatment strategies, address age-related variability and bridge gaps in acute and invasive care while ensuring safety and efficacy in this population.
Keywords: Acute Coronary Syndrome, Elderly, Risk Factors, Coronary Artery Disease, Clinical Profile, Dyslipidemia, Hypertension, Mortality
How to Cite?: Dr. Darshana Makwana, Dr. Yogini Babubhai Nalwaya, Dr. Neelima, Dr. Kanzariya Umesh Mohan, "Aging Hearts at Risk: Clinical Spectrum and in-Hospital Mortality in Geriatic Acute Coronary Syndrome", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 1212-1216, https://www.ijsr.net/getabstract.php?paperid=SR26709181945, DOI: https://dx.doi.org/10.21275/SR26709181945