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Original Research | General Surgery | Volume 15 Issue 7, July 2026 | Pages: 1878 - 1882 | India
Association of Helicobacter Pylori Infection and Surgical Outcomes in Gastroduodenal Perforation: A Prospective Comparative Study of Graham's Patch and Modified Graham's Patch Repair
Abstract: Background: Gastroduodenal perforation due to acid peptic disease remains a major emergency surgical condition, particularly in resource-limited settings. Helicobacter pylori infection is an important etiological factor in peptic ulcer disease, while the choice of operative repair may influence postoperative recovery. This study evaluated the association of H. pylori infection with gastroduodenal perforation and compared outcomes between Graham's Patch Repair and Modified Graham's Patch Repair. Aim: To determine the prevalence of H. pylori infection among patients with gastroduodenal perforation and compare the postoperative outcomes of Graham's Patch Repair and Modified Graham's Patch Repair. Materials and Methods: This prospective comparative study was conducted in the Department of Surgery, B.R.D. Medical College, Gorakhpur, from 2024 to 2026. A total of 114 patients with gastroduodenal perforation and peritonitis undergoing operative intervention were included. Patients with suspected malignant perforation, traumatic perforation, penetrating abdominal injury, or refusal of consent were excluded. Patients underwent either Graham's Patch Repair or Modified Graham's Patch Repair. H. pylori status was assessed using available intraoperative diagnostic methods. Postoperative complications, duration of hospital stay, time to resume oral feeding, recurrence and mortality were compared between groups. Data were analysed using appropriate statistical tests, with p
Keywords: Helicobacter pylori, Gastroduodenal perforation, Graham's Patch Repair, Modified Graham's Patch Repair, Peptic ulcer disease, Surgical outcome
How to Cite?: Dr. Prakarsh Gupta, Dr. Sandesh Kumar Srivastava, Dr. Durgesh Kumar Tripathi, Dr. Kushagra Kumar, "Association of Helicobacter Pylori Infection and Surgical Outcomes in Gastroduodenal Perforation: A Prospective Comparative Study of Graham's Patch and Modified Graham's Patch Repair", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 1878-1882, https://www.ijsr.net/getabstract.php?paperid=SR26707162323, DOI: https://dx.doi.org/10.21275/SR26707162323