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Comparative Study | Anaesthesiology | Volume 15 Issue 6, June 2026 | Pages: 1155 - 1160 | India
Haemodynamic and Recovery Characteristics in Conventional versus Sequential Extubation Using Sugammadex as a Reversal Agent: A Prospective Randomized Comparative Study
Abstract: Background and Aims: Extubation during emergence from general anaesthesia is associated with significant haemodynamic fluctuations and airway-related complications. Sequential extubation using a supraglottic airway device may attenuate these responses. This study compared haemodynamic and recovery characteristics between conventional extubation and sequential extubation using sugammadex for neuromuscular reversal. Methods: This prospective, randomized, comparative study involved 140 adult patients scheduled for elective surgery under general anaesthesia. Participants were randomly assigned to two equal groups: Group C, which received conventional tracheal extubation, and Group S, which underwent sequential extubation utilizing an I-gel supraglottic airway device. Haemodynamic parameters, that include heart rate (HR) and blood pressure (BP), were recorded at baseline and at 0, 5, 10, 15, and 30 minutes post-extubation. Recovery outcomes had been assessed with the help of the Modified Aldrete Score. Results: Sequential extubation was associated with significantly lower HR and mean arterial pressure (MAP) at all post-extubation time-points (P < 0.001). Group S demonstrated faster recovery with a shorter time to train-of-four ratio ≥0.9, shorter time to extubation, higher Modified Aldrete scores at post-anaesthesia care unit arrival, and shorter post-anaesthesia care unit stay duration. No cases of laryngospasm or severe desaturation were observed in the sequential extubation group. Conclusion: Sequential extubation using sugammadex was associated with improved haemodynamic stability, faster recovery, and fewer airway-related complications compared with conventional extubation.
Keywords: Sugammadex, Airway Management, Tracheal Extubation, Laryngeal Masks, Haemodynamics, Recovery of Function
How to Cite?: Dr. Shalini Bhardwaj, Dr. Shahbaz Ahmad, Dr. Mahtab Alam, Dr. Satish Kumar, Dr. Sunil Kumar Arya, "Haemodynamic and Recovery Characteristics in Conventional versus Sequential Extubation Using Sugammadex as a Reversal Agent: A Prospective Randomized Comparative Study", Volume 15 Issue 6, June 2026, International Journal of Science and Research (IJSR), Pages: 1155-1160, https://www.ijsr.net/getabstract.php?paperid=SR26614131920, DOI: https://dx.doi.org/10.21275/SR26614131920