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Review Paper | Psychology Science | Volume 15 Issue 7, July 2026 | Pages: 2159 - 2164 | India
The Gut-Brain Axis and Anxiety Disorders: A Review of Clinical and Psychological Perspectives
Abstract: This review examines the bidirectional relationship between the Gut-Brain Axis and anxiety disorders, with emphasis on Generalized Anxiety Disorder. Current evidence demonstrates significant clinical overlap between anxiety disorders and disorders of gut-brain interaction, supported by alterations in gut microbial diversity and composition. Patients with anxiety frequently exhibit reduced beneficial microbial populations and increased potentially pathogenic bacteria, suggesting persistent biological dysregulation beyond psychological symptoms alone. Emerging microbiome-based interventions, including probiotics, prebiotics, and dietary modulation, show promising therapeutic potential; however, robust randomized controlled trials are required before routine clinical implementation. Overall, current evidence supports a biopsychosocial understanding of anxiety and highlights the Gut-Brain Axis as an important target for future research and treatment.
Keywords: Gut-Brain Axis, Microbiome, Anxiety Disorder, Generalized Anxiety Disorder (GAD), Dysbiosis, Probiotics, Comorbidity, Gut-Brain Interaction
How to Cite?: Prajusha Giri, Shifa Maimunah, "The Gut-Brain Axis and Anxiety Disorders: A Review of Clinical and Psychological Perspectives", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 2159-2164, https://www.ijsr.net/getabstract.php?paperid=SR26609152801, DOI: https://dx.doi.org/10.21275/SR26609152801