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Case Report | Obstetrics and Gynecology | Volume 15 Issue 5, May 2026 | Pages: 1654 - 1656 | India
Balancing Blood and Bump: A Case Report on Aplastic Anemia in Pregnancy
Abstract: Introduction: Aplastic anemia refers to the syndrome of hematopoietic failure from injury leading to diminished or absent hematopoietic precursors in the bone marrow and resultant pancytopenia. During pregnancy it could be life-threatening for both mother and child. The only causal therapy for aplastic anemia is bone marrow transplantation, which is contraindicated during pregnancy because of potential embryo toxicity. Hence, Treatment options are erythrocytes and platelet transfusions and immunosuppressive therapy. Case Presentation: This is a case of a 30 year old G5P3L2D1SA1 who came to our OPD at 31weeks of gestation with severe anemia (Hb- 6.2g/dl). Patient was diagnosed with Aplastic anemia 4 years back, (at P3L2D1, all FTND with cu-T insitu) and was lost to follow up. She was managed with multiple blood products transfusion, close consultation with Hematology and a maintenance therapy of immunosuppressants and thrombopoetin agonists that she responded to. This case report discusses on managing the complications that were encountered during her antenatal course and averting a catastrophic clinical deterioration using a multidisciplinary approach of management. Conclusion: Aplastic anemia when juxtaposed with pregnancy can be life-threatening. The seriousness depends on the degree of bone marrow suppression. During severe aplastic anemia or complications caused by the supportive therapy (erythrocyte and platelet transfusions and antibiotics) Anti-Thymocyte Globulin (ATG), methylprednisolone and/or Cyclosporine A could be started.
Keywords: Aplastic anemia, Pregnancy, Cyclosporine A, Anti-thymocyte globulin, Eltrombopag, Danazol
How to Cite?: Dr Manasi Tamhane, Dr. Hemangi J Kansaria, "Balancing Blood and Bump: A Case Report on Aplastic Anemia in Pregnancy", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 1654-1656, https://www.ijsr.net/getabstract.php?paperid=SR26524153754, DOI: https://dx.dx.doi.org/10.21275/SR26524153754