Pattern of Organ Failure in Acute Pancreatitis: A Cross-Sectional Study from Northeast India

Rupankar Nandi, Ajit Kumar Pegu, Rashmi Rajkakati

Abstract: Background: Organ failure is the principal determinant of severity and mortality in acute pancreatitis. This study evaluated the frequency and pattern of respiratory, renal, and cardiovascular failure and their in-hospital outcomes. Methods: This hospital-based cross-sectional observational study with prospective in-hospital outcome ascertainment included 40 consecutive adults with acute pancreatitis admitted to Assam Medical College and Hospital, Dibrugarh, from October 2024 to September 2025. Acute pancreatitis was diagnosed using the Revised Atlanta criteria. Organ failure was defined as a Modified Marshall score of at least 2; dysfunction persisting for more than 48 hours was classified as persistent organ failure. Exact tests were used for exploratory comparisons. Results: Organ failure occurred in 12 patients (30.0%). Respiratory failure was the most frequent pattern (10/40, 25.0%), followed by renal failure (8/40, 20.0%) and cardiovascular failure (3/40, 7.5%). Seven patients (17.5%) had multiple-organ failure and 7 (17.5%) had persistent organ failure. All 12 patients with organ failure required intensive care, compared with none without organ failure (p

Keywords: acute pancreatitis, organ failure, persistent organ failure, Modified Marshall score, respiratory failure, multiple organ dysfunction

How to Cite?: Rupankar Nandi, Ajit Kumar Pegu, Rashmi Rajkakati, "Pattern of Organ Failure in Acute Pancreatitis: A Cross-Sectional Study from Northeast India", Volume 15 Issue 8, August 2026, International Journal of Science and Research (IJSR), Pages: 47-50, https://www.ijsr.net/getabstract.php?paperid=SR26521084931, DOI: https://dx.doi.org/10.21275/SR26521084931

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