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Original Research | Oncology Science | Volume 15 Issue 5, May 2026 | Pages: 345 - 351 | India
Demographic Association of Laterality and Histopathology in Metastatic Colorectal Carcinoma Patients
Abstract: Colorectal cancer becomes third most fatal cancer type and leads to high mortality rates in India as well as worldwide. For proper prognosis and management detection of tumour staging is necessary. In this research paper concluded histopathological aspect of metastatic colorectal carcinoma (mCRC). In this four-year histological study included 51 forth stage colorectal cancer patents were selected. Tissue sample was received from biopsy procedure followed by immediate preservation in formalin solution. After tissue section preparation using microtomy apparatus diagnosis was given according to TNM staging. Fifty-one patients of IV stage colorectal cancer were examined during the period of January 2022 to December 2025. Patients with more than 18 years of age groups were selected. Tissue sample were selected using biopsy sampling and types of malignancy were diagnosed. Most of the patients showed left side laterality (72.55%) and 42 (76.47%) of patients had Adenocarcinoma (NOS) histology followed by mucinous and signet ring adenocarcinoma (15.69% and 7.84% respectively). The most common symptoms are abdominal pain (41.17%) and bleeding per rectum (33.33%). The study of colorectal carcinoma in Hadoti region conclude that the mean age of the patients is 58 ? 0.24 (in male) 54 ? 0.45 (in female) and proportion of male is slightly higher than the female. Adenocarcinoma lesion and left laterality was more common in TNM staging criteria.
Keywords: Biopsy, TNM staging, Adenocarcinoma, colorectal cancer, malignancy, rectal bleeding
How to Cite?: Boskey Pancholi, Harish Gautam, R K Tanwar, Manish Gautam, "Demographic Association of Laterality and Histopathology in Metastatic Colorectal Carcinoma Patients", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 345-351, https://www.ijsr.net/getabstract.php?paperid=SR26504205222, DOI: https://dx.doi.org/10.21275/SR26504205222