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Review Papers | Neurology | Volume 15 Issue 4, April 2026 | Pages: 359 - 362 | India
Role of Ommaya Reservoir in the Management of Cystic Craniopharyngioma: A Review of Therapeutic Outcomes
Abstract: Craniopharyngiomas are benign epithelial tumors of the sellar region characterized by high recurrence rates and significant cystic components. This review evaluates the role of Ommaya reservoir placement and intracystic bleomycin therapy in the management of cystic variants. A synthesis of clinical approaches including stereotactic catheter placement, cyst aspiration, and intracystic chemotherapy was performed, with reported dosing ranging from 2 to 5 mg per injection at intervals of 2 to 7 days and cumulative doses between 15 and 180 mg. Evidence indicates that intracystic bleomycin effectively reduces cyst volume, stabilizes tumor progression, and facilitates subsequent surgical intervention, with long-term control observed in 43 to 73 percent of cases. Complications such as infection, catheter malposition, and neurotoxicity were reported but remained manageable. These findings suggest that Ommaya reservoir based intracystic therapy represents a valuable minimally invasive adjunct, particularly in pediatric and recurrent cases, although standardized protocols and long-term outcome data are needed.
Keywords: Craniopharyngioma, cystic craniopharyngioma, Ommaya reservoir, intracystic chemotherapy, bleomycin therapy, pediatric neurosurgery
How to Cite?: Dr. Ved Prakash Maurya, Dr. Swarjith Nimmakayala, Dr. Amit Agrawal, "Role of Ommaya Reservoir in the Management of Cystic Craniopharyngioma: A Review of Therapeutic Outcomes", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 359-362, https://www.ijsr.net/getabstract.php?paperid=SR26405003455, DOI: https://dx.dx.doi.org/10.21275/SR26405003455