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Original Article | Psychiatry | Volume 15 Issue 3, March 2026 | Pages: 1424 - 1428 | India
Prevalence and Clinical Correlates of Thrombocytopenia among Inpatients with Alcohol Dependence Syndrome: A Retrospective Cross-Sectional Study in a Tertiary Psychiatry Setting
Abstract: Background: Alcohol Dependence Syndrome is associated with hematological abnormalities including thrombocytopenia, yet its clinical correlates in psychiatric inpatient settings remain insufficiently studied. Objective: To determine the prevalence of thrombocytopenia and examine its association with dependence severity, withdrawal severity, and liver function parameters. Methods: A retrospective cross-sectional study analyzed records of 102 inpatients aged 18 to 65 years. Platelet counts, liver function tests, Severity of Alcohol Dependence Questionnaire scores, and Clinical Institute Withdrawal Assessment scores were evaluated using chi square test, Welch t test, and Spearman correlation. Results: Thrombocytopenia was identified in 18.63 percent of patients, predominantly mild to moderate. A significant association was observed with dependence severity, while no association was found with withdrawal severity or liver function indices. Platelet count showed a weak negative correlation with dependence severity. Conclusion: Thrombocytopenia is a clinically relevant abnormality associated with cumulative alcohol exposure. Routine platelet monitoring may support risk stratification during inpatient detoxification.
Keywords: Alcohol Dependence Syndrome, Thrombocytopenia, Platelet Count, SADQ, CIWA-Ar, Liver Function Tests, Alcohol withdrawal, Hematological abnormalities, and Psychiatric inpatient detoxification
How to Cite?: Anukriti Garg, Purushotham A, Mohan Reddy M, Ruth Sneha, "Prevalence and Clinical Correlates of Thrombocytopenia among Inpatients with Alcohol Dependence Syndrome: A Retrospective Cross-Sectional Study in a Tertiary Psychiatry Setting", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1424-1428, https://www.ijsr.net/getabstract.php?paperid=SR26322180428, DOI: https://dx.dx.doi.org/10.21275/SR26322180428