A Preliminary Study on the Anthelminthic Activity of Methanolic Extract of Hibiscus Sabdariffa var.rubra

M. Sangamithirai, B. Thiripurasundari

Abstract: Helminthiasis is a macro parasitic disease of humans and animals in which a part of the body is infested with parasitic worms such as pinworm, roundworm, or tapeworm. Typically, the worms reside in the gastrointestinal tract but may also burrow into the liver or other organs. Anthelmintics or anthelminthics are drugs or agents that destroy or cause the expulsion of parasitic intestinal worms. Treatment with an anthelminthic drug kill worms whose genotype renders them susceptible to the drug. Herbal remedies are considered the oldest forms of health care known to mankind on this earth. The parts of plants used for medicinal purposes are leaves, root, stem, fruits, the complete aerial parts, the whole plant, barks (root and stem) and flowers. However, leaves were found as the most frequently used part. Traditional system of medicine reports the efficacy of several natural plants in eliminating worms. The aim of the present study was to investigate the anthelminthic activity of Hibiscus sabdariffa leaf extract using adult earthworm, lubricant. The methanolic extract of the crude extract at concentrations of 1mg/ml, 2mg/ml, 4mg/ml, 8mg/ml were tested which involve determination of paralysis time and death time. Albendazole was used as standard and it was found that the concentrated methanolic extract (with no traces of solvent) of the Hibiscus sabdariffa leaves which is used as food in many parts of the world, showed a better anthelminthic activity in comparison with the standard. Further studies may be carried out to isolate the bioactive compound responsible for the anthelminthic activity.

Keywords: Anthelminthic activity, Albendazole, Earthworm, Hibiscus sabdariffa

How to Cite?: M. Sangamithirai, B. Thiripurasundari, "A Preliminary Study on the Anthelminthic Activity of Methanolic Extract of Hibiscus Sabdariffa var.rubra", Volume 14 Issue 10, October 2025, International Journal of Science and Research (IJSR), Pages: 1550-1555, https://www.ijsr.net/getabstract.php?paperid=SR25921202303, DOI: https://dx.doi.org/10.21275/SR25921202303