Screening of Secondary Metabolites and their Antioxidant Activity of Cassia fistula Linn.

Thenmozhi N., Chitra M.

Abstract: Extracts obtained from the dried stem and leaves of Cassia fistula Linn. belonging to Leguminosae family have been tested for screening of secondary metabolites and antioxidant activity. The phytochemical properties of C. fistula has shown a variety of useful properties like blood sugar levels regulation, control of tumor cell proliferation, infertility and inflammation. The results on antioxidant activity indicated that there were higher levels of total phenolics (177.03 mg GAE/g extract), tannins (166.16 mg GAE/g extract), flavonoids (190.17 mg RE/g extract) and DPPH radical scavenging activity in the ethanol extract of the leaf compared to the aqueous ethyl acetate extract. There was a high level of antioxidant activity in the stem ethanol extract (31.28 ?g/mL), as well as in the stem aqueous extract (148333 ?m TE/g), ferric reducing power leaf ethanol extract (99.07 mM Fe (II) E/mg extract), phosphomolybdenum assay (153.3 AAE/g), and nitric oxide (59.57 %) in the in vitro antioxidant measurements. The antioxidant activity of C. fistula leaf extracts is quite impressive, making them a very good substance for pharmaceutical product development and a potential natural source for new therapeutic agents.

Keywords: Cassia fistula, secondary metabolites, antioxidant activity

How to Cite?: Thenmozhi N., Chitra M., "Screening of Secondary Metabolites and their Antioxidant Activity of Cassia fistula Linn.", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 1138-1144, https://www.ijsr.net/getabstract.php?paperid=SR25807130137, DOI: https://dx.doi.org/10.21275/SR25807130137