Pharmacological & Toxicological Interactions (with Alcohol): A Critical Study on Drug-Drug Interactions; (DDIs with Ethanol) & Its detection through Advance Forensic Practices. An Evolving Subspeciality of Forensic Pharmacovigilance & Polypharmacy

Pithadia Rajat R, Shailee Thakur

Abstract: The purpose of this paper is to throw light on modern and advance methods for detection of DDIs in forensic practice. It shares insights on the interactions of drugs with alcohol and its adverse effects. This research is intended to bring in-depth study of few compounds & its effect on human body, symptoms, measures to counteract it & its methods of detection. This is developed through reviewing many different literatures of different sources and coagulated to form a paper of specialized drug interaction. In modern polypharmacy; which is a relatively new approach; where combination and integration of drugs are used from its vector positions and summation of its effects on the human body. This shall also aid in medical science but also gives a weapon to the criminal minded people in the society. Our idea is to spread awareness and bring some meaningful measures to fight these criminal tendencies by enumerating information on how such crimes are facilitated and how such crimes can be prevented. The main body of this report is divided into 3 major parts. The first part deals with all the information about interaction of drugs. The second part deals completely with alcohol and its pharmacology, as it is our object drug of research. The third part is further divided into 3 sub-parts; where we critically asses 2 cases of interaction of alcohol: (i) Marijuana-Nicotine; & (ii) LSD. At the end of our research, we shall conclude our findings to establish some critical evidences and modern procedures.

Keywords: Drug-drug interaction, cannabis (THC) interaction with alcohol and nicotine, polypharmacy, forensically relevant interactions, pharmacological interactions

How to Cite?: Pithadia Rajat R, Shailee Thakur, "Pharmacological & Toxicological Interactions (with Alcohol): A Critical Study on Drug-Drug Interactions; (DDIs with Ethanol) & Its detection through Advance Forensic Practices. An Evolving Subspeciality of Forensic Pharmacovigilance & Polypharmacy", Volume 14 Issue 6, June 2025, International Journal of Science and Research (IJSR), Pages: 1052-1078, https://www.ijsr.net/getabstract.php?paperid=SR25614110820, DOI: https://dx.doi.org/10.21275/SR25614110820