Giant Liposarcoma of the Thigh: A Rare Case of 20 Year Evolution

Dr. Balamurali Krishnan, Dr. Ambikavathy M., Dr. Anusha, Dr. Vivithashree

Abstract: Introduction: Giant well-differentiated liposarcoma (WDL) is a rare soft tissue sarcoma subtype, often misdiagnosed due to its indolent behavior and resemblance to benign lipomas. Case Presentation: We report the case of a 46-year-old woman with a 20-year history of a slowly growing thigh mass that showed sudden enlargement over the preceding two months. MRI suggested a lipomatous tumor with malignant potential. Surgical excision was performed, and histopathology confirmed a well-differentiated liposarcoma. Outcome: The patient underwent wide local excision with primary closure and had an uneventful postoperative recovery. Conclusion: This case emphasizes the importance of considering malignancy in long-standing soft tissue masses, especially with recent changes, and the value of imaging and histopathology in guiding treatment.

Keywords: well-differentiated liposarcoma, soft tissue sarcoma, diagnostic imaging, histopathology, surgical management

How to Cite?: Dr. Balamurali Krishnan, Dr. Ambikavathy M., Dr. Anusha, Dr. Vivithashree, "Giant Liposarcoma of the Thigh: A Rare Case of 20 Year Evolution", Volume 14 Issue 5, May 2025, International Journal of Science and Research (IJSR), Pages: 877-881, https://www.ijsr.net/getabstract.php?paperid=SR25513233730, DOI: https://dx.doi.org/10.21275/SR25513233730