Understanding Non-Ossifying Fibroma or Chondroid Myxoid Fibroma: Causes, Diagnosis, And Challenges

Dr. Vaibhav Bhatta, Dr Nimesh Agrawal, Dr. Ganesh Avhad, Dr. Madan Manmohan

Abstract: Non-ossifying fibromas (NOFs) are common lesions most frequently found in the growing bones of children and adolescents. Although NOFs are benign, their presence as incidental findings often triggers further investigation as they are sometimes mistaken for more sinister bone lesions such as aneurysmal bone cysts. NOFs can also pose an increased risk of pathological fractures. However, there are currently no guidelines on the follow-up of NOFs. We present a case series of five patients from Addenbrooke?s Hospital with NOFs illustrating their morphological features on plain radiographs and highlighting specific characteristics to support clinicians in diagnosing and managing NOFs. Chondromyxoid fibroma (CMF) is a rare benign bony tumour. Our objectives are three-fold: first, comparing MRI, conventional radiography (CR) and CT characteristics of CMF; second, providing a literature review; and third, summarizing the role of imaging landmarks in the differential diagnosis with other bony lesions.

Keywords: non-ossifying fibroma, bone lesion, paediatric orthopedics

How to Cite?: Dr. Vaibhav Bhatta, Dr Nimesh Agrawal, Dr. Ganesh Avhad, Dr. Madan Manmohan, "Understanding Non-Ossifying Fibroma or Chondroid Myxoid Fibroma: Causes, Diagnosis, And Challenges", Volume 14 Issue 5, May 2025, International Journal of Science and Research (IJSR), Pages: 570-573, https://www.ijsr.net/getabstract.php?paperid=SR25508102859, DOI: https://dx.doi.org/10.21275/SR25508102859