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Experimental Result Paper | Chemistry | Volume 14 Issue 4, April 2025 | Pages: 2408 - 2413 | India
Synthesis and ADMET-Evaluation of Oxadiazole and Pyrazolone Derivatives
Abstract: Hydrazides and hydrazones are important molecules for synthesizing numerous heterocyclic compounds. These heterocycles show important biological activities. This research work leads to synthesize pyrazolone and oxadiazole derivatives from hydrazides-hydrazones through cyclization reaction using different reagents. These compounds were screened in silico ADMET properties to evaluate their bio-chemical studies by using online mode ADMET Lab 3.0. These in silico ADMET evaluation results suggests that, the compounds show good chemical ADMET properties, indicating their potential for safe and effective use and it also provide a comprehensive toxicity profile needed for development of therapeutic agents.
Keywords: Hydrazide, hydrazone, pyrazolone, oxadiazole, ADMET properties
How to Cite?: Vijay J. Desale, "Synthesis and ADMET-Evaluation of Oxadiazole and Pyrazolone Derivatives", Volume 14 Issue 4, April 2025, International Journal of Science and Research (IJSR), Pages: 2408-2413, https://www.ijsr.net/getabstract.php?paperid=SR25427164440, DOI: https://dx.doi.org/10.21275/SR25427164440