Phytochemical Investigation and In-Vitro Anti-Deppressant Activity of Albizia Lebbeck

Basavaraj Chivade, Padma s Sagar, Nagendrakumar Dhumansure

Abstract: The plant Albizia lebbeck is a species of the family Fabaceae. Native to Indian subcontinent and Myanmar. It is widely cultivated and naturalized in other tropical and subtropical regions, including Australia. Albizia lebbeck plant was selected because of its therapeutic uses, the part used was leaves. The leaves of Albizia lebbeck were extracted using maceration and soxhlet extraction process and yield obtained was 2mg and 86.23mg respectively, so soxhlet extraction gives better yield when compared with maceration. By invitro assay method the methanolic extract of Albizia lebbeck leaves produced better Anti depressant activity against PC12 and C6 cell lines, which is supported by increased cell viability from inducing leaves extract of Albizia lebbeck on PC12and C6 cell lines.

Keywords: Albizia lebbeck, Fabaceae, Invitro, viability, cell lines