Exploring the Role of Zolpidem in Managing Insomnia in Hypertensive Patients: An Expert Panel Insights Review

Samir Kubba, Ketan Mehta, Pradeep Kumar

Abstract: This narrative review examines the bidirectional relationship between insomnia and hypertension, drawing an insights from an expert panel convened in May 2024 in India. It explores the prevalence of insomnia among hypertensive patients, its impact on cardiovascular risk through mechanisms like non - dipping blood pressure, and the therapeutic role of Zolpidem. Based on a focused group discussion with 11 eminent physicians and cardiologists, the review highlights the efficacy of Zolpidem in improving sleep quality, reducing sympathetic overactivity, and potentially lowering blood pressure in this population. The discussion underscores the need for targeted insomnia management in hypertensive patients to mitigate cardiovascular risks, offering practical clinical insights supported by literature and expert consensus.

Keywords: Insomnia, Hypertension, Zolpidem, Nondipping Blood Pressure, Cardiovascular Risk