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Research Paper | Pharmaceutical Science | India | Volume 14 Issue 4, April 2025 | Popularity: 4.9 / 10
Formulate and Evaluate Myrobalan Powder Incorporated Chocolate Drug Delivery System
Sachin Verma, Mounitha Sathish, Muthuraj V
Abstract: Myrobalan scientifically known as Terminalia chebula is a very popular and one of the important herbal materials employees in traditional system of medicine in India especially Ayurveda. It is reported to have anti - oxidant, anti - microbial, antidiabetic, anticarcinogenic, antiviral, anti - bacteria, antifungal, etc. activities and is recommended to be consumed 1 - 2 g once or twice a day as Ayurveda Pharmacopoeia. The intact fruit is very hard. The powdered pericarp is unpleasant in colour and taste. myrobalan in commercially available as (powder, lozenges, churna) yet there is a continuous need to formulate more reliable delivery methods. In this work myrobalan powder is being tried to be incorporated in chocolate drug delivery system. The present study aims to development and evaluation of myrobalan powder incorporated chocolate drug delivery system. In this work initially pre - formulation studies were carried out which includes particle size analysis, flow properties of powder and phytochemical screening. The formulation of myrobalan incorporated chocolate is prepared by using active ingredient as myrobalan powder and other ingredients such as, cocoa butter, cocoa powder, preservative and sweeting agent. The six different formulation varieties were developed as F1, F2, F3, F4, F5 and F6. The evaluation test was carried out by TLC, Hardness test, Thickness test and stability studies. Myrobalan powder could successfully be incorporated in the chocolate base. White chocolate and dark chocolate were tried F6 was found to be ideal for delivery of myrobalan powder.
Keywords: Terminalia chebula, Extraction, TLC plate, hardness, thickness, stability chamber, chocolate drug delivery system
Edition: Volume 14 Issue 4, April 2025
Pages: 637 - 641
DOI: https://www.doi.org/10.21275/SR25321093559
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