Synthesis, Characterization, and Anti-Mycobacterial Evaluation of Oxadiazole and Pyrazolone Derivatives

Vijay J. Desale, Ramesh S. Yamgar

Abstract: Hydrazides and hydrazones are important precursors for synthesizing heterocyclic compounds. This study focuses on the synthesis and characterization of pyrazolone and 1,3,4-oxadiazole derivatives using spectroscopic techniques. These compounds were screened for their anti-mycobacterial activity, showing promising results. Additionally, in silico ADMET predictions were performed to evaluate their chemical properties. The results indicate the potential of these derivatives as effective anti-tuberculosis agents, paving the way for further biological evaluations.

Keywords: Hydrazide, hydrazone, oxadiazole, pyrazolone, anti-tuberculosis

How to Cite?: Vijay J. Desale, Ramesh S. Yamgar, "Synthesis, Characterization, and Anti-Mycobacterial Evaluation of Oxadiazole and Pyrazolone Derivatives", Volume 14 Issue 2, February 2025, International Journal of Science and Research (IJSR), Pages: 1241-1244, https://www.ijsr.net/getabstract.php?paperid=SR25219221505, DOI: https://dx.doi.org/10.21275/SR25219221505