Regenerative Therapy for Peri-Implantitis: Clinical Evaluation and Theoretical Insights into Collagen-Based OsGrowth Application

Lei Ge, Ying Wang, Hui Sun, Lixin Xu

Abstract: This study reviews 68 recent publications on regenerative treatments for peri-implantitis and analyzes three clinical cases involving Chenggu Kuai® OsGrowth, a collagen-based bone graft material. Traditional regenerative materials often suffer from low osseointegration and poor degradation synchrony. In contrast, Chenggu Kuai® OsGrowth demonstrates enhanced clinical efficacy, with follow-up data indicating new bone formation rates of 65% to 88%. The study introduces a novel conceptual model- "collagen scaffold, angiogenesis, and inflammation regulation" - to explain the material's therapeutic potential. Findings suggest that Chenggu Kuai® OsGrowth offers a viable, clinically promotable solution for moderate to severe peri-implantitis. This article aims to evaluate the effectiveness of Chenggu Kuai® OsGrowth in the treatment of peri-implantitis through literature analysis and clinical case studies, while proposing a new theoretical model for collagen-based regenerative mechanisms.

Keywords: Peri-implantitis, Collagen scaffold, Bone regeneration, OsGrowth, Dental implant therapy

How to Cite?: Lei Ge, Ying Wang, Hui Sun, Lixin Xu, "Regenerative Therapy for Peri-Implantitis: Clinical Evaluation and Theoretical Insights into Collagen-Based OsGrowth Application", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 1967-1975, https://www.ijsr.net/getabstract.php?paperid=SR251216083615, DOI: https://dx.doi.org/10.21275/SR251216083615