Sodium Fluoride Alter Architecture of Intestine and Kidney of Fresh Water Fishes Labeo rohita

M. D. Kale

Abstract: The present study was conducted to investigate the histological structures of the intestine and kidneys of fresh water fish Labeo rohita after short (96 hrs) and long term exposure (30 days) in sodium fluoride ( NaF) (46.75ppm). Several histological alternations were obtained in the intestine and Kidney. In intestine damages internal villi of intestine, mucosal layer showed necrosis resulting into degeneration of cells at few places. Sub-mucosa showed hypertrophy and vacuolation of cells. Beginning of sloughing of mucosal layer is evident from the formation of a gap between mucosal and sub-mucosal layers. In chronic the villi tends to become flattened, and there is sloughing of the mucosal lining. The disorganization of sub-mucosa and formation of vacuolated areas. In kidneys severe degenerative and necrosis changes in the renal tubule with focal area of necrosis, haemorrhage between renal tubule and edema in Bowman?s capsule with atrophy in the glomeruli. The necrosis of the renal tubule affects the metabolic activities and promotes metabolic abnormality have been observed. Kidney is responsible for excretion of polluting agents brought after detoxification in liver.

Keywords: histological changes, sodium fluoride exposure, intestinal degeneration, renal damage, Labeo rohita

How to Cite?: M. D. Kale, "Sodium Fluoride Alter Architecture of Intestine and Kidney of Fresh Water Fishes Labeo rohita", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 674-678, https://www.ijsr.net/getabstract.php?paperid=SR251208172814, DOI: https://dx.doi.org/10.21275/SR251208172814