Primary Squamous Cell Carcinoma at Proximal Tibia: A Rare Case Report

Dr. Jyoti Singh, Dr. Reena Jain, Dr. Jyoti Priyadarshini, Dr. Sudha Iyengar

Abstract: Introduction: Primary squamous cell carcinoma of bone is rare in the skeletal system. The majority of these carcinomas when found in the extremities are metastatic from another primary. Case Summary: We report a case of 40 year female presented with complain of right sided knee pain, tenderness since 3 month, insidious in onset also having difficulty in weight bearing there was no history of trauma and fever previously. Pain was aggravated on movement and reduced on taking rest or on medication. The excised tissue was sent for histopathological examination for histopathological examination in our department. Conclusion: This report is the first to describe primary keratinizing SCC of the tibial bone. However, there is still no consensus on the standard treatment method or prognosis of primary SCC of non-skull bones because of its rarity, with only a few cases having been reported and followed up. Our findings demonstrate that clinicians must exhaust all available means for the diagnosis of primary SCC of bones, so greater attention can be paid to timely treatment and effective management.

Keywords: Keratinizing SCC, Proximal Tibia, p63, Histopathological examination

How to Cite?: Dr. Jyoti Singh, Dr. Reena Jain, Dr. Jyoti Priyadarshini, Dr. Sudha Iyengar, "Primary Squamous Cell Carcinoma at Proximal Tibia: A Rare Case Report", Volume 14 Issue 11, November 2025, International Journal of Science and Research (IJSR), Pages: 1967-1969, https://www.ijsr.net/getabstract.php?paperid=SR251121133024, DOI: https://dx.doi.org/10.21275/SR251121133024