Synthesis, Spectral Characterization, Thermal Behavior and Biological Studies of Co(II), Cu(II), Mn(III) and Fe(III) Metal Complexes of Schiff Base Ligand

S. B. Rathod, P. R. Mandlik

Abstract: N'-((E)-4-bromobenzylidene)-2-((E)-2-hydroxybenzylidene) hydrazine-1- carbothiohydrazide and its metal complexes with Co(II), Cu(II), Mn(III), and Fe(III) were synthesized. The synthesized complexes were characterized using infrared spectra, 1H NMR, thermal studies and elemental analysis. Molar conductance analysis reveals that none of the developed complexes was naturally electrolytes. The weight change as a function of temperature was used to calculate the complexes' free energy, activation energy, and reaction pattern. The synthesized ligand and its complexes exhibited significant antimicrobial activity.

Keywords: Thiocarbohydrazone, Metal complexes, Infra-red, 1H NMR, Thermal Study, Antibacterial activity