Standardization and Phytochemical Evaluation of the Unani Formulation Dawa-e-Hilteet in Pill and Majoon Dosage Forms

Qudsia Zehra, Ghulamuddin Sofi

Abstract: Unani system of medicine was based on humoral theory of Buqarat. Drugs are used in single form as well as in compound form. There is a need to standardized formulation according to some parameters for providing evidence-based medicine with purity and efficacy. Dawa-e-Hilteet is a classical Unani formulation traditionally used in treating fever (Humma). This formulation had not been standardized to date. This study aims to standardize the formulation in two dosage forms-Majoon and Pills-by evaluating physicochemical properties, phytochemical composition, safety profile, and active constituents using pharmacopoeial protocols and GC-MS analysis. Dawa-e-Hilteet was a formulation of four ingredients Ferula asafoetida (Hilteet), Commiphora myrrha (Mur Makki), Piper nigrum (Filfil Siyah) and Ruta graveolens (Suddab). The results of study showed acceptable results for heavy metals and microbial contamination. GC-MS revealed 68 phytochemical constituents. The findings provide a foundational reference for further studies, promoting the evidence-based application of this Unani formulation.

Keywords: Dawa-e-Hilteet, Unani medicine, Standardization, Phytochemical analysis, GC-MS

How to Cite?: Qudsia Zehra, Ghulamuddin Sofi, "Standardization and Phytochemical Evaluation of the Unani Formulation Dawa-e-Hilteet in Pill and Majoon Dosage Forms", Volume 14 Issue 10, October 2025, International Journal of Science and Research (IJSR), Pages: 1412-1418, https://www.ijsr.net/getabstract.php?paperid=SR251024224042, DOI: https://dx.doi.org/10.21275/SR251024224042