Chlorpromazine-Induced Ocular Toxicity: A Rare Case with Corneal, Lenticular, and Retinal Involvement

Dr. Rajvin Samuel, Dr. Jayashree Rebecca

Abstract: Purpose: To report a rare case of chlorpromazine-induced ocular toxicity with corneal, lenticular, and retinal involvement. Methods: Case report of a 47-year-old female with long-term chlorpromazine use, evaluated with multimodal imaging. Results: Findings included corneal granular deposits, anterior subcapsular cataracts, and ellipsoid zone loss on OCT. The cumulative dose was approximately 2400 g. Conclusion: Chronic chlorpromazine therapy can cause significant ocular toxicity. Routine screening and early drug modification are crucial to preserve vision.

Keywords: Chlorpromazine toxicity, Ocular changes, Corneal deposits, Retinal involvement, Drug-induced cataract

How to Cite?: Dr. Rajvin Samuel, Dr. Jayashree Rebecca, "Chlorpromazine-Induced Ocular Toxicity: A Rare Case with Corneal, Lenticular, and Retinal Involvement", Volume 14 Issue 10, October 2025, International Journal of Science and Research (IJSR), Pages: 1098-1099, https://www.ijsr.net/getabstract.php?paperid=SR251020195536, DOI: https://dx.doi.org/10.21275/SR251020195536