Investigation of Ternary Nickel (II) Complexes with Amino Acids and Diols: Stability, Biological Implications, and Structural Insights

Shraddha Shukla

Abstract: The synthesis, stability, and possible uses of ternary complexes of nickel (II) with histidine, adenine, and other diols or amino acids are investigated in this work. Potentiometric techniques were used to establish stability constants, exposing patterns based on coordination environments and ligand structures. Increased stability in compounds with ? - electron systems or aromatic ligands points to important roles in environmental and biological processes. These discoveries open the door for uses in catalysis and medication development by shedding light on nickel's function in enzymes and its interactions with biological macromolecules.

Keywords: Ternary complex, nickel, amino acids, Potentiometric techniques, ligand, catalysis and medication