Clinical Study to Evaluate the Efficacy of Maharasnadi Kvatha, Trayodashanga Guggulu, and Brihatsaindhavadya Taila in the Management of Knee Osteoarthritis (Janugata Sandhivata
Abstract: Introduction: Osteoarthritis (OA) is the progressive musculoskeletal disorder that characterized by the gradual and persistent degradation of cartilage tissue within joints due to bone friction. The risk factors associated with the development of OA include the female gender, advanced age (geriatric population), elevated body weight or obesity, and a history of a prior knee injury. Ayurveda therapy has great potential in the management of OA and its progression. Aim: This clinical study aims to assess the effect of selected Ayurveda formulations in the management of knee OA. Materials and Methods: This was a prospective, single - center, open - label study carried out on 60 participants with primary OA of the knee. Inclusion criteria encompassed individuals aged between 35 and 65 years, meeting the diagnostic criteria outlined by the American College of Rheumatology, and with radiographic abnormalities characteristic of OA. Therapeutic interventions in the study comprised Maharasnadi Kvatha (MK) (50?mL twice a day in an empty stomach), Trayodashanga Guggulu (TG) (1500?mg twice daily), and Brihatsaindhavadya Taila (BST) (for local fomentation twice daily) for the duration of 84 days. The primary outcome of the study was change in the Indian Western Ontario and McMaster Universities arthritis index (WOMAC) score. Results: Out of 60 participants, 58 subjects completed the study, while one subject dropped out and one was withdrawn. The analysis yielded statistically significant results (P
Keywords: Brihatsaindhavadya taila, Janugata sandhivata, Maharasnadi kvatha, osteoarthritis of knee, Trayodashanga guggulu
How to Cite?: Dr. Samiksha Sharma, "Clinical Study to Evaluate the Efficacy of Maharasnadi Kvatha, Trayodashanga Guggulu, and Brihatsaindhavadya Taila in the Management of Knee Osteoarthritis (Janugata Sandhivata", Volume 13 Issue 9, September 2024, International Journal of Science and Research (IJSR), Pages: 1257-1263, https://www.ijsr.net/getabstract.php?paperid=SR24917141542, DOI: https://dx.doi.org/10.21275/SR24917141542