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Research Paper | Medicinal Plants | India | Volume 13 Issue 9, September 2024 | Popularity: 6 / 10
Antibiotic Susceptibility Patterns of Periodontal Bacteria in Diabetic vs Non - Diabetic Individuals
Pooja Jha, Vandana
Abstract: Introduction: Periodontitis is a chronic inflammatory disease that compromises the supporting structures of teeth, often exacerbated in individuals with diabetes mellitus, a metabolic disorder marked by chronic hyperglycemia. This study aimed to analyse the susceptibility patterns of periodontitis - causing microorganisms in diabetic and non - diabetic patients, with a focus on antibiotic resistance. Methodology: Dental plaque specimens were collected from 100 patients with varying dental health statuses, including those with diabetes and dental caries. Bacterial isolates from the plaque samples were cultured on different media, identified based on morphological and biochemical tests, and subjected to antibiotic susceptibility testing using the Kirby - Bauer method. Statistical analysis: The study utilized descriptive statistics to determine the prevalence of bacterial isolates and their resistance patterns to antibiotics. The frequency of resistance among bacterial species was compared between diabetic and non - diabetic groups, and potential factors influencing these patterns were analysed. Results: Out of the 100 dental plaque samples, 70 exhibited bacterial growth. Gram - positive bacteria, particularly Porphyromonas gingivalis and Tannerella forsythia, were predominant. The antibiotic susceptibility test revealed high resistance rates to amoxicillin and cefotaxime among Gram - positive isolates. The findings highlight significant antibiotic resistance among periodontitis - causing bacteria, particularly in diabetic patients, underscoring the need for targeted treatment strategies and further research to explore factors influencing microbial susceptibility.
Keywords: Susceptibility, Hyperglycemia, Antibiotic resistance, Diabetes mellitus
Edition: Volume 13 Issue 9, September 2024
Pages: 593 - 597
DOI: https://www.doi.org/10.21275/SR24910120048
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