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Analysis Study Research Paper | Chemistry | India | Volume 13 Issue 7, July 2024 | Popularity: 5.4 / 10
Biological Study of Synthesised E/Z-4, 5-Dihydro Spiro [3-Phenyl-5-Substituted Phenyl Isoxazole-4, 4' (2',4'-Dihydro-5'-Methyl-2'-Phenyl/ Phenyl Methyl-3'h-Pyrazol-3'-Ones)]
Vipin Kumar Singh, Vijay Pratap Singh, Amrendra Kumar Singh
Abstract: A study on biological activity of synthesized [E-(3a-e) and Z-(3a-e)] spiro isoxazole-pyrazolone derivatives. This examination by single spore isolation and disc diffusion method shows that all compounds have antimicrobial activity. The compounds 3d (E/Z) shows best antibacterial activity against Gram positive bacteria Staphylococcus aureus, Bacillus subtilis, Gram negative bacteria Pseudomonas aeruginosa, Escherichia coli and antifungal activity against Aspergillus niger.
Keywords: Spiro isoxazole-pyrazolones, Antibacterial activity, Inhibition zones, Single spore isolation, Disk diffusion
Edition: Volume 13 Issue 7, July 2024
Pages: 307 - 310
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