Evaluating the Association of Serum Zinc Levels with Hepatic Encephalopathy in Decompensated Chronic Liver Disease Patients in Teritiary Care Center

Nandam Madhuri, C. Prabhakar Raju, Gujjula Sidhartha

Abstract: Hepatic Encephalopathy is the term used to describe the complex and variable reversible changes in neuropsychiatric status in patient with chronic liver disease. It is defining feature of the fulminant hepatic failure. Zinc is a trace element which is an important cofactor of urea cycle enzymes like ornithine transcarboxylase, and others like glutamine synthetase which are essential for conversion of ammonia to urea. This study presents a remarkable insight of association of zinc levels with hepatic encephalopathy which helps as marker of investigation and helps in management and future therapeutic approaches.

Keywords: Hepatic Encephalopathy (HE), Decompensated Chronic Liver Disease, DCLD