Impact of Oocyte Retrieval Number on Cumulative Live Birth Rates in ICSI Cycles: A Retrospective Study
Abstract: Aim: To study the association between the number of oocytes retrieved and cumulative live birth rates (CLBR) Design: Retrospective analysis of patients who underwent autologous first ICSI cycle. Setting: Institute of Reproductive Medicine, Madras Medical Mission Hospital, Chennai. Methods: Patients undergoing first ICSI cycle from January 2017 to December 2019. The study included 275 patients who were grouped based on the number of oocytes retrieved (30). They were further sub grouped into categories based on their age, BMI and AMH. The cumulative LBR was calculated on per - retrieval basis and was defined as at least 1 live (more than 28 weeks) birth from all linked embryo frozen transfers. Result: The cumulative LBR increased rapidly with the number of oocytes retrieved up to 10, plateaued from 11 - 15 oocytes, after which there were diminishing returns. Conclusion: GnRH Antagonist stimulation with 10 - 15 oocytes had a cumulative LBR of 66.7% in the first IVF cycle with frozen embryo transfers. Beyond 15 oocytes, the CLBR declined.
Keywords: Oocyte retrieval, Cumulative Live Birth Rate, ICSI, IVF, Reproductive medicine
How to Cite?: Abinaya Duraisingam, Kundavi Shankar, Yamini Asokan, Geetha V, Rashmi G. V, Nithya Naaram, Hema Niveda K. R, "Impact of Oocyte Retrieval Number on Cumulative Live Birth Rates in ICSI Cycles: A Retrospective Study", Volume 13 Issue 5, May 2024, International Journal of Science and Research (IJSR), Pages: 1764-1767, https://www.ijsr.net/getabstract.php?paperid=SR24528121425, DOI: https://dx.doi.org/10.21275/SR24528121425