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Student Project | Obstetrics and Gynecology | India | Volume 13 Issue 3, March 2024
Study of Ovarian Reserve Parameters among Women Suffering from Secondary Subfertility Presenting in Infertility Clinic in a Tertiary Health Care Centre in Eastern India: A Prospective Observational Study
Dr. Shreeja Singh [2] | Dr. Ankit Kumar [2]
Abstract: Background and Aim: Unexplained subfertility is diagnosed when standard tests for ovulation, tubal patency and semen analysis are all normal. overall incidence is 30%. We aimed to assess the availability of a test capable of providing reliable information regarding a woman's individual ovarian reserve within a certain age category. Methods: from January 2018 till June 2018, 100 females in OPD underage group between 20-35 years, suffering from secondary subfertility were selected. The collected data was analyzed using descriptive (mean, median, & standard deviation) and inferential statistics and results are presented using diagrams, graphs, and tables. The relationship between parameters i.e., AGE, BMI, Menstrual abnormality, Ovarian reserve parameters like D2 FSH, LH, AMH & antral follicular count were tested using Kruskal-Wallis?s test (non-parametric test). Results: Out of 100 females in OPD, mean age was the mean age of the female partner was 32?2.7 years and that of male partner was 39?4.2 years. The variable Age (Years) was normally distributed in the 2 subgroups (Primary and secondary infertility). The mean age being highest in the secondary infertility group (t = -4.817, p = < 0.001). In terms of BMI, 54% were overweight and 37% of overweight group had primary subfertility and 67% had secondary subfertility. The following variables were significantly associated (p<0.005) with the variable 'Age (Years)?: Complain, Obstetric History, Age Group, Period of Infertility (Years), Menstrual History, Day 2 AFC (Right Ovary), Day 2 AFC (Left Ovary), Peripherally Arranged Follicles, D2 FSH, AMH. Among the 100 couples suffering from secondary subfertility, 26% cases were tubal, 51% PCOD, 15% were ovulatory and 8% cases had endometriosis and that among women with PCOD more incidence is seen in women with secondary subfertility vs primary subfertility (54% vs 46%). Conclusion: We concluded that Overall FSH is most used screening tool for DOR, AFC and AMH exhibit less variability and are therefore promising tools. Currently there is no uniformly accepted definition of DOR.
Keywords: subfertility, ovarian reserve, age, BMI, infertility
Edition: Volume 13 Issue 3, March 2024,
Pages: 1004 - 1009