International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Review Papers | Medicine | Kenya | Volume 13 Issue 5, May 2024 | Rating: 4.8 / 10


Clinical Insights and Therapeutic Advancements: The Evolving Role of Magaldrate in Gastrointestinal Health

P N Ritesh


Abstract: Magaldrate, a widely used antacid agent, has been a cornerstone in the management of various gastrointestinal disorders for decades. Its unique chemical composition and mechanism of action contribute to its efficacy in neutralizing gastric acid and providing symptomatic relief. This article provides a comprehensive review of the pharmacological properties, clinical applications, safety profile, and future perspectives of magaldrate. The mechanism of action involves neutralization of gastric acid, formation of a protective coating over the gastric mucosa, and inhibition of pepsin activity. Clinical studies have demonstrated its efficacy in conditions such as peptic ulcer disease, gastroesophageal reflux disease, dyspepsia, and gastritis. Magaldrate exhibits a favorable safety profile, with minimal adverse effects reported. Future research directions include exploring its potential applications in novel therapeutic areas, advancements in formulation and drug delivery systems, and personalized medicine approaches. Overall, magaldrate remains a valuable therapeutic option in the management of gastrointestinal disorders, offering effective relief and gastroprotective effects.


Keywords: Magaldrate, antacid, gastrointestinal disorders, mechanism of action, clinical applications


Edition: Volume 13 Issue 5, May 2024,


Pages: 545 - 549


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