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Comparative Studies | Biochemistry | India | Volume 13 Issue 2, February 2024

A Study of Serum C - Reactive Protein, Uric Acid and Lipid Profile in Patients with Psoriasis Visiting Dermatology Department, PBM Hospital, Bikaner

Dr. Neha Suthar

Abstract: Introduction: Psoriasis is an autoimmune proliferative skin condition characterized itchy skin rashes, red scalps on the skin. It is a chronic, painful, disfiguring and disabling disease for which there is no cure and with great negative impact on patients, it can occur at any age, and is most common in the age group 50 - 69 years. Aim and Objective: To analyse serum levels of Uric acid, C - Reactive Protein and Lipid Profile in Psoriasis Patients. Material and Methods: This was an Hospital base case - control study carried out in Department of Biochemistry, Department of Dermatology in collaboration with Department of Microbiology, Rajasthan. The 100 consecutive cases were included for the study. Result: The 10% subjects as normal control group belong to age 18 - 30 years, 30% subjects belong to 31 - 40 years, 24% subjects belong to 41 - 50 years, 16% subjects belong to 51 - 60 years, 20% subjects belong to 61 - 75 years. The serum CRP level varies from 0.3 to 1.0 mg/dl with a mean 0.51?0.16 mg/dl in normal control subjects. The mean serum uric acid level is found to be 4.81?1.05 mg/dl with a range of 2.5 to 6.8 mg/dl in control subjects. Conclusion: The results of present study showed that in psoriasis patients serum C - reactive protein, uric acid, cholesterol, triglycerides, LDL - cholesterol, VLDL - cholesterol was significantly increased and serum HDL - cholesterol level were significantly reduced. So, it gives us a clue regarding possible relation of above parameters in psoriasis patients.

Keywords: CRP, Uric acid, Lipid Profile, Psoriasis

Edition: Volume 13 Issue 2, February 2024,

Pages: 1841 - 1843