Exploring Protein Biomarkers in Cancer: A Bioinformatics Approach

Pinki, Rita Singh

Abstract: Cancer is a leading cause of deaths worldwide. There are many clinically available biomarkers for its diagnostics and therapeutics. In our study, we demonstrate bioinformatics as an important tool in evaluating the potential of protein biomarkers. By utilizing Expasy ProtParam tool, we identify key molecular characteristics, including half - life, molecular weight, isoelectric point (pI), etc. and SOPMA is utilized for examining the secondary structure composition. Moreover, the protein - protein interaction of each selected biomarker is investigated using STRING analysis to mark functional relevance of selected biomarkers. Our findings underscore the multifaceted capabilities of bioinformatics tools in evaluating diverse aspects of protein biomarkers.

Keywords: Biomarkers, Bioinformatics, Expasy Protparam tool, SOPMA, STRING