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India | Hematology | Volume 13 Issue 2, February 2024 | Pages: 1391 - 1392
Association of Solitary Tumors in Polycythemia Vera with 3p Deletion
Abstract: The association of JAK2 (Janus kinase-2) V617F mutation in myeloproliferative neoplasms has long been established. We report a case of a 48 years old male a known case of JAK 2 positive polycythemia vera presenting with anaemia who was incidentally detected to have carcinoma of distal stomach. His cytogenetic study revealed 3p deletion which is said be associated with both haematological and solitary tumors. Hence we emphasise the importance of cytogenetics in diagnosis and prognosis of patients with both haematologicalsolitary malignancies.
Keywords: Polycythemia Vera, JAK2 V617F, 3p deletion, Gastric cancer
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