Comparative Efficacy of Nebulized 3% Hypertonic Saline Versus 0.9% Normal Saline in Children with Acute Bronchiolitis: A Randomized Clinical Trial

Neha Nizar N, Arasarseeralar

Abstract: In this randomized clinical trial, we compared the efficacy of nebulized 3 hypertonic saline versus normal saline in children aged 3 to 24 months diagnosed with acute bronchiolitis. Our findings suggest that while both treatments are safe, 3 hypertonic saline may offer benefits in reducing hospital stay duration without significantly affecting clinical severity or the need for additional nebulizations. Further research is necessary to confirm these outcomes and explore potential mechanisms.

Keywords: acute bronchiolitis, hypertonic saline, nebulization, pediatric respiratory diseases, randomized clinical trial