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Research Paper | Radiology and Medical Imaging Sciences | India | Volume 13 Issue 2, February 2024
Impact of T2* MR Cartigraphy in Knee Joint Osteoarthritis
Ashwini Sankhe Sonve | Jernail Singh Bava [4] | Shubhi Goyal | Yugal Goyal
Abstract: Background: MRI allows direct visualization of all tissues involved in osteoarthritis disease process including articular cartilage. In addition to morphologic assessment, MRI-based techniques have been developed that allow characterization and quantification of biochemical composition of cartilage. We have focussed on T2* mapping in our study. Objective: To study and grade changes in knee joint cartilage in various stages of osteoarthritis and to evaluate role of MR cartigraphy in early diagnosis of osteoarthritis. Methods: A retrospective and prospective observational study of 45 patients at a tertiary care centre referred for knee pain who presented during period of July 2020 to January 2023 using Philips 3T Ingenia MRI machine. Results: All patients in our study with Kellgren-Lawrence (KL) grade 0 and 1 (n=5) had raised T2* value (p value <0.001). T2* values increase with higher grade of osteoarthritis. Conclusion: T2* mapping helps in detecting early cartilage degeneration, even when grey scale MRI yields normal results. Clinical Impact: In order to start treatment early and track course of disease in osteoarthritis, it is crucial to diagnose cartilage damage before it is detected by conventional sequences that find morphological cartilage lesions when cartilage has already irreversibly damaged. This can be achieved with T2* mapping.
Keywords: Cartigraphy, Knee joint. MRI, Osteoarthritis, T2, mapping
Edition: Volume 13 Issue 2, February 2024,
Pages: 975 - 981