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Review Papers | Dentistry | India | Volume 13 Issue 2, February 2024

Stem Cells in Periodontal Regenerations - A Review

Dr. Arunagiri Karunanithi | Dr. Arulvizhi M | Dr. Srinivasan K

Abstract: The regeneration of periodontal tissues is considered a promising strategy.Stem cells have remarkable properties, such as immunomodulatory potential, proliferation, migration, and multilineage differentiation. Thus, they can be used to repair tissue damage andreduce inflammation, potentially leading to periodontal regeneration. Among the stem cells used forperiodontal regeneration, we studied dental mesenchymal stem cells (DMSCs), non-dental stem cells,and induced pluripotent stem cells (IPSCs). Although these cells have well-documented importantphysiological characteristics, their use in contemporary practice to repair the affected periodontiumis still a challenge.Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of periodontal tissues,are found in the periodontal ligament (PDL). These cells have long been referred to as mesenchymalstem/stromal cells (MSCs), and their clinical applications have been extensively studied.

Keywords: Stem cells; periodontal regeneration; dental mesenchymal stem cells;non-dental stem cells; induced pluripotent stem cells

Edition: Volume 13 Issue 2, February 2024,

Pages: 589 - 594