Clinical, Histopathological, and Serological Comparisons between Primary and Secondary Sjogren's Syndrome

Nazeh Sh Mustafa, Raja Kummoona, Mohammed H Al Osami, Ziad S. Al Rawi

Abstract: This study compares the clinical, serological, and histopathological characteristics of primary Sj?gren's Syndrome (pSS) and secondary Sj?gren's Syndrome (sSS) in Iraqi patients. Conducted at Medical City Hospital / Baghdad over two years, it enrolled 218 pSS and 207 sSS patients. Key findings include significant differences in parotid gland enlargement, arthritis, and serological markers between the groups. These results highlight the distinct clinical profiles of pSS and sSS, contributing to better diagnostic and treatment approaches.

Keywords: Sjogren?s syndrome, primary Sjogren?s syndrome, secondary Sjogren?s syndrome, parotid gland enlargement, autoimmune disease