Study of Uric Acid Level in Newly Diagnosed Hypertensive Patients in Tertiary Care Centre, Barabanki
Abstract: Background: The "quiet executioner" moniker for hypertension (HTN) comes from the fact that the condition often goes undiagnosed and unnoticed by its victims. The presence of high amounts of uric acid can cause an overexpression of both of these vasoconstrictor molecules, leading to the development of hypertension. Additionally, uric acid can mediate the onset of hypertension via a crystal - dependent mechanism. Evidence of monosodium urate deposits has been reported in various organs and tissues, including the renal medulla, heart valves, arteries, and atherosclerotic plaque. Aim: To study association between newly diagnosed hypertensive patients and their serum uric acid levels. Materials and Method: The study conducted at Dr KNS Memorial Institute of Medical Sciences, Barabanki involved patients with newly diagnosed hypertension and normotensive individuals. The research was a case - control study that lasted from August 2022 to February 2024, with a sample size of 150 (75 cases and 75 controls). Upon obtaining informed consent, The patients underwent investigations for systolic and diastolic blood pressure, as well as serum uric acid levels. Guidelines were followed for measuring blood pressure, including posture, avoidance of caffeine and smoking, and ensuring a quiet, warm setting. Results: Study suggestive of Grade 1 hypertension (40%) was common grade reported in our study. Apart from this; high normal (32%) and grade 2 (28%) was also reported. The mean value of lipid profile parameters like total cholesterol (195.07 v/s 171.09; p
Keywords: Hypertension, Hyperuricemia, Uric Acid
How to Cite?: Dr. Nikhil Rathi, Dr. Sundaram Kumar, Dr. (Col) Anil Kumar Pawah, "Study of Uric Acid Level in Newly Diagnosed Hypertensive Patients in Tertiary Care Centre, Barabanki", Volume 13 Issue 11, November 2024, International Journal of Science and Research (IJSR), Pages: 1570-1575, https://www.ijsr.net/getabstract.php?paperid=SR241126081351, DOI: https://dx.doi.org/10.21275/SR241126081351