Clinicoetiological and Radiological Correlation in Patients Presenting with Noncompressive Myelopathy

Dr. Krishnapriya M R, Dr. S. Sivakumar, Dr. Thiruvaruthchelvan, Dr. Praveen Singh Peter, Dr. K S Raja

Abstract: Background: Non - compressive myelopathy encompasses a large range of disease entities ranging from demyelination, infection, nutritional, toxic, hereditary - familial to degenerative conditions. With the advent of MRI which is a very sensitive modality for the intramedullary spinal lesions it has become pertinent to have a relook at the profile of non - compressive myelopathies in India. In this paper we want to present our experience with various non - compressive myelopathies and its radiological correlation. Aim: To study the clinical spectrum of non - compressive myelopathy and clinicoradiological correlation Objective: To study the clinical spectrum of patients with non - compressive myelopathy. Duration: 1 year. Methodology: Prospective observational study of patients in outpatient department of neurology dept GMKMCH Salem Results: Out of 30 patients with non - compressive myelopathy acute transverse myelitis was the commonest (15) followed by vitamin B12 defy (4) followed by hereditary spastic paraplegia (3) paraneoplastic myelopathy (2) HIV myelopathy (1). No etiology can be found out in remaining 5 cases. The most common abnormality detected in MRI was hyperintense lesions that occupy the central core. CSF done in ATM done showed rise in proteins with minimal pleocytosis. Conclusion: Acute transverse myelitis is the leading cause of non - compressive myelopathy. Clinical features combined with MRI findings are helpful in defining the cause of ATM.

Keywords: Non compressive myelopathy, Acute transverse myelitis, NMOSD (neuromyelitis Optica Spectrum Disorder), AQP4 antibody

How to Cite?: Dr. Krishnapriya M R, Dr. S. Sivakumar, Dr. Thiruvaruthchelvan, Dr. Praveen Singh Peter, Dr. K S Raja, "Clinicoetiological and Radiological Correlation in Patients Presenting with Noncompressive Myelopathy", Volume 13 Issue 11, November 2024, International Journal of Science and Research (IJSR), Pages: 452-454, https://www.ijsr.net/getabstract.php?paperid=SR241106213228, DOI: https://dx.doi.org/10.21275/SR241106213228