Systematic Review and Meta-Analysis of the Efficacy of PICO Dressing in Wound Management

Adham Sadoon Hamad

Abstract: Background: A standardized electronic PICO dressing was developed to ensure a moist wound-healing environment. This review had to look at its effectiveness compared to standard dressings. Aims: To assess healing rates, infection rates, and general patient acceptability in patients with a variety of wound types receiving the PICO system vs standard care dressing. Methods: We performed a systematic search in databases, including PubMed, Cochrane Library, and Scopus for studies related to ellagic published up to October 2023. These were the PICO Randomized Controlled Trials (RCTs) compared to standard dressings. Meta-analysis was conducted using random effects models. Results: Ten studies including 1200 patients fulfilled the inclusion criteria. Regarding the secondary outcomes, PICO dressing significantly shortened the time to healing (SMD = ?1.23 days, 95% CI: ?1.75 to-0.71; p < 0.001) and reduced infection rates compared with Standard dressings (RR = 0.56, 95% CI: 0.41 to?5%; certainty of evidence=very low). Conclusion: PICO dressing is superior to standard dressings in wound healing and reduction of infection rates. These findings need to be confirmed in a larger number of patients.

Keywords: PICO Dressing; Meta-Analysis; Wound Infection; Systemic Review; Wound Management