The Role of Dentist in Early diagnosis of Odontohypophosphatasia - A Clinical Case Report

Laiali I. Aladwan, Ferdous A. Alrahamneh, Rayeh M. Alrashed, Zain Alsharaf Y. Atiyat, Dima M. Alotoom

Abstract: Hypophosphatasia is a genetic disorder that happens very rarely. It affects the way bones and teeth mineralize and is accompanied by a lack of tissue-nonspecific alkaline phosphatase activity in both serum and bone tissues. The estimated prevalence of severe manifestations of the disease is 1 in every 100,000 individuals. Individuals who exhibit dental manifestations characterized by the premature loss of primary teethwithout any accompanying systemic symptomsare categorized as having odontohypophosphatasia. This case report will outline the presentation of a three-year-old male patient who sought treatment at our clinic due to premature loss of primary teeth.

Keywords: Hypophosphatasia, Odontohypophosphatasia, OdontoHPP, Alkaline phosphatase, TNSAP

How to Cite?: Laiali I. Aladwan, Ferdous A. Alrahamneh, Rayeh M. Alrashed, Zain Alsharaf Y. Atiyat, Dima M. Alotoom, "The Role of Dentist in Early diagnosis of Odontohypophosphatasia - A Clinical Case Report", Volume 12 Issue 10, October 2023, International Journal of Science and Research (IJSR), Pages: 63-66, https://www.ijsr.net/getabstract.php?paperid=SR23928011328, DOI: https://dx.doi.org/10.21275/SR23928011328