To Compare the Effect of Instrument Assisted Proprioceptive Training versus Conventional Proprioceptive Training on Peripheral Neuropathy and Balance in Colorectal Cancer Subjects Following Oxaliplatin Chemotherapy - A Comparative Study
Abstract: Background: Peripheral neuropathy and loss of balance following oxaliplatin chemotherapy are major challenges facing colorectal cancer subjects as a side effect of the chemotherapeutic agent.It damages various cells in different ways, leading to neuropathy through a complex interaction among sensor cells, neurons, glial cells, and effector cells. These alterations in nerve function led to impaired reception, transmission, and response to stimuli, which consequently affect one's tactile sensory perception, inappropriate proprioceptive feedback, and hence impaired postural control and loss of balance in this subject. Aim: To study and compare the effects of instrument-assisted proprioceptive training using a modified trampoline with conventional proprioceptive training on peripheral neuropathy and balance in colorectal cancer subjects following oxaliplatin chemotherapy. Subjects and Methods: A total of 90 colorectal cancer subjects aged between 41 and 60 who have completed 12 cycles of oxaliplatin chemotherapy were selected by the convenience sampling method. In this comparative study, subjects were divided into Group A (n = 45) for instrument-assisted proprioceptive training and Group B (n = 45) for conventional proprioceptive training for 4 weeks. The pre- and post-assessment of peripheral neuropathy and balance was done using the FACT-GOG-NTX scale and the Brief BEST test, respectively. Results: There was an extremely significant difference in peripheral neuropathy and balance between groups post-treatment (p
Keywords: oxaliplatin, peripheral neuropathy, balance, proprioception. modified trampoline
How to Cite?: Pruthvika Holmukhe, Trupti Yadav, "To Compare the Effect of Instrument Assisted Proprioceptive Training versus Conventional Proprioceptive Training on Peripheral Neuropathy and Balance in Colorectal Cancer Subjects Following Oxaliplatin Chemotherapy - A Comparative Study", Volume 12 Issue 9, September 2023, International Journal of Science and Research (IJSR), Pages: 1805-1811, https://www.ijsr.net/getabstract.php?paperid=SR23916115438, DOI: https://dx.doi.org/10.21275/SR23916115438