Outcomes of Children Presenting with Signs of Early Puberty to a Tertiary Pediatric Endocrinology Service

Dr. Mai Ali, Dr. Talat Mushtaq

Abstract: The aim of this study is to review the outcomes for children who present with early puberty symptoms to a tertiary paediatric endocrinology clinic. There are two main aims: 1) Documenting the number of children who were considered to have a variation of puberty (eg. premature adrenarche, thelarche) or a pathological diagnosis (eg, central precocious puberty, congenital adrenal hyperplasia (CAH) or a gonadal tumour). 2) Review the initial and subsequent investigations to assess if there is scope to focus or rationalise the investigations in conjunction with initial clinical findings.

Keywords: Precocious puberty, Clinical presentations, Diagnostic challenges, Long-term implications, Pediatric endocrinology