International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Masters Thesis | Health Sciences | Kenya | Volume 12 Issue 9, September 2023

Factors Affecting Adherence to HIV Post-Exposure Prophylaxis among Victims of Rape and Defilement in Vihiga County, Kenya

Elizabeth Mmbone

Abstract: Sexual assault, particularly rape and defilement, is a global public health problem. Vihiga County, with a high HIV/AIDS prevalence, reports high rates of these crimes. There is high HIV transmission risk after rape, necessitating HIV Post-Exposure Prophylaxis (PEP) use. However, most victims don?t seek or complete the treatment. This study in Vihiga County, Kenya assessed PEP adherence among sexual assault victims and influencing factors. The research used a descriptive cross-sectional design at three healthcare facilities, focusing on victims seeking care in 2021. Data collection involved interviews with healthcare providers and a review of medical records. Analysis methods included percentages, tables, thematic analysis, Pearson's Chi-square test, and simple linear regression.74.4% of victims were under 19, with 68.3% being adolescents (10-19). Victim age significantly affected PEP adherence (p = 0.018). PEP adherence was positively associated with drug side effects, pill burden, and lost follow-up (p < 0.001). Adherence barriers included side effects, pill burden, stigma, lack of support, and service coordination issues. Adolescents and school-going children were at higher risk of both sexual assault and PEP non-compliance. Study recommended promotion of post-rape care and PEP awareness in schools and communities and development of low-side-effect PEP regimens, preferably a single-dose option.

Keywords: Sexual assault, HIV PEP, Adherence

Edition: Volume 12 Issue 9, September 2023,

Pages: 943 - 950

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