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Doctoral Thesis | Life Sciences | India | Volume 12 Issue 9, September 2023

Antioxidant and Free-Radical-Scavenging Activity of Sarcostemma Brevistigma, Wight & Arn.- An Ethnomedicinal Plant

Dr. S. M. Dhivya | Dr. S. Sharmila | Dr. P. Abirami | Dr. P. Vijayashalini

Abstract: The plant Sarcostemma brevistigma (family-Asclepiadaceae) commonly known as "Kodikali" is used in many ayurvedic formulations. The present study was designed to evaluate the in vitro antioxidant potential of an ethanolic extract of Sarcostemma brevistigma. In vitro antioxidant activity was carried out by the reducing power assay, DPPH radical scavenging activity, Hydroxyl radical scavenging activity, Nitric oxide radical inhibition assay, Superoxide radical scavenging activity, Phosphomolybdenum assay and Determination of total phenolic content. The antioxidant activities of the study plant were found to increase with an increase in concentration. The extract exhibited the maximum reductive capacity, which was more or less equivalent to standards. The ethanolic extract (10, 20, 40, 60, 80 & 100 ?g/ml) was compared with Ascorbic acid and Quercetin as a standard. The results of the present study clearly indicated that an ethanolic extract of Sarcostemma brevistigma possesses powerful in vitro antioxidant activity.

Keywords: Sarcostemma brevistigma, free radicals, reducing power assay, phospohomolybdenum assay and Quercetin

Edition: Volume 12 Issue 9, September 2023,

Pages: 560 - 574