Deep Vein Thrombosis in Tuberculosis Patients: A Study of Two Cases

Dr. Swati Soni, Dr. Gurpreet Sharma, Dr. Sapna Kaushish, Dr. Ajay Sharma, Dr. Ravi Sharma, Dr. Rajesh Bhawani

Abstract: Deep vein thrombosis DVT has been observed in 1.5 - 3.4 % of tuberculosis TB cases. Identifying TB patients at high risk of venous thromboembolism VTE is crucial. The presented study highlights two cases of DVT complicating TB, emphasizing the importance of early diagnosis and management using antitubercular drugs and anticoagulants. The mechanism behind DVT development in TB remains unclear, but factors like increased plasma fibrinogen, factor VIII, and reactive thrombocytosis may contribute. Additionally, the association between rifampicin - containing regimens and DVT risk is examined, and the efficacy and safety of NOAC agents in thromboembolism prevention and treatment are discussed.

Keywords: Deep Vein Thrombosis, Tuberculosis, Venous Thromboembolism, Antitubercular Drugs, Anticoagulation