Clomiphene Citrate in Obesity - Associated Hypogonadism

Mateus Andrade Misson, Carlos Oliveira Leal Neto, Lucas Querino Wirz, Daniel Martins Borges, Thalita Leal Leite Pimenta

Abstract: This study investigates the benefits of Clomiphene Citrate CC in treating obesity-associated secondary hypogonadism. An integrative review was conducted, focusing on pharmacodynamic principles, risk-benefit, safety, and therapeutic effectiveness. The study concludes that CC is a safe and effective therapy for hypogonadotropic hypogonadism, especially beneficial for those desiring fatherhood.

Keywords: Hypogonadism. Male Obesity, ClomiphenCitrat. Fertility, Hypothalamic-Pituitary-Gonadal Axis